Ultimately, the treatment differences don't seem that meaningful, even if the authors were able to observe statistical significance with the somewhat over-manipulated method of analysis. The revisions include the addition of methodological detail, modified language to reflect the nuance of some of the measurements, as well as re-performed experiments with more appropriate control groups. The findings in this report may improve in vitro conditions to overcome this problem, as well as add important physiological context to the role of reproductive tract glandular secretions in modulating sperm behaviors. The authors have added methodological details and re-performed experiments with more appropriate control groups, enhancing the robustness of the study. Nucleotide sequence data reported are available in the DDBJ Sequenced Read Archive under the accession number DRA017090. Since researchers did not collect new human data or specimens, no additional ethical review was required based on Hiroshima University's policy.
